St Marylebone C of E School is a secondary school for girls in Marylebone, London. It specialises in Performing Arts, Maths & Computing. In the sixth form, boys can also attend. On 1 September 2011 the school became a converter academy having previously been judged "outstanding in every respect" by Ofsted.
Founded in 1791, St Marylebone Church of England School is now a multi-faith comprehensive school for girls aged from eleven to eighteen. The main site is located just behind St Marylebone Parish Church, with the Sixth Form Centre based in another building in nearby Blandford Street.